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This site provides some highlights of the work and play of Frank Delaglio. In the scientific community, Frank is best known for being the developer of NMRPipe, a software system for analysis of multidimensional Nuclear Magnetic Resonance (NMR) spectral data. As of this year, NMRPipe has been cited more than 6,000 times in peer-reviewed scientific journals. Frank continues to participate in academic research on applications of NMR to biomolecular analysis.

Multidimensional NMR is the primary method used to study the structure and interactions of proteins and other biomolecules in solution. This is important for several reasons. For one, most all functions of living cells are performed by proteins and nucleic acids interacting with other molecules, and many of these functions, such as reproduction, or converting nutrients to usable forms of energy, are common to all forms of cellular life. For another, many disease states are associated with the function or misfunction of proteins, and as such, most drugs work by interacting with a single protein or class of proteins.

Frank's commercial work emphasizes development of software applications for science and industry, including imaging applications, molecular structure calculation, automation, and NMR screening tools for one-dimensional and two-dimensional spectral series analysis. These screening applications are commonly applied to drug discovery and optimization.

Fellow pipers can have a look at the NMRPipe Reference Page, a comprehensive list of programs, functions, and scripts in NMRPipe.

Frank is now a Manager of NMR Software Products in the Life Sciences Group of Agilent Technologies.

Frank's 2011 presentations included:

    EMBO Course on Protein Dynamics and Function, July 29 - Aug 5
    NANUC NMR Bootcamp, Edmonton Canada, Aug 15 - 20

Frank's 2012 presentations include:

    2012 ENC Miami, at the Agilent User's Meeting, April 15 - 19
    NANUC NMR Bootcamp, Toronto Canada, June 4 - 9

The first version of this site was posted on May 31, 2006. It was last updated on April 19, 2012.

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Site last updated: Apr 19, 2012 / big fd

Contact site designer mimi at mdelaglio@hotmail.com